| Name | Description (Nemesis) | Description (Boss) |
| Agile | Enemies start at the top of the Action Queue. | Enemies start at the top of the Action Queue and have an independent 50% chance to dodge attacks. |
| Blessed | Enemies start with 5 buffs. | Enemies start with 10 buffs. |
| Blinking | Your creatures' spells deal 90% less damage. | Your creatures' spells deal 90% less damage. |
| Brutal | Enemies deal 100% more damage and always deal critical damage. | Enemies deal 100% more damage, always deal critical damage, and ignore 50% of your creatures' Defense. |
| Champion | Leader is immune to damage, debuffs, and stat reduction while its allies are alive. | Leader is immune to damage, debuffs, and stat reduction while its allies are alive. |
| Feedback | Your creatures take damage equal to 1% of their Maximum Health for each Mana they spend. | Your creatures take damage equal to 3% of their Maximum Health for each Mana they spend. |
| Hearty | Enemies have 100% more Health and take 50% less damage. | Enemies have 100% more Health and take 50% less damage. |
| Hex | Your creatures' artifacts are decayed. | |
| Horde | When enemies die, new enemies come to replace them. | After enemies die, new enemies come to replace them. |
| Greedy | Enemies drop extra items. | |
| Genius | You and your creatures gain 30x the normal amount of experience points from defeating these creatures. | |
| Knowledgeable | You gain 50x the normal amount of Knowledge from defeating these creatures. | |
| Macabre | Your creatures start with 3 debuffs. | Your creatures start with 5 debuffs. |
| Misery | Your creatures cannot heal, resurrect, or gain buffs or stats. | Your creatures cannot heal, resurrect, or gain buffs or stats. |
| Obtuse | Your creatures' attacks deal 90% less damage. | |
| Plague | Your creatures are afflicted with a random debuff at the start of their turns. | Your creatures are afflicted with a random debuff a tthe start and end of their turns. |
| Protected | Enemies cannot take damage that exceeds more than 25% of their Maximum Health. | Enemies cannot take damage that exceeds more than 15% of their Maximum Health. |
| Pulse | Your creatures take damage equal to 20% of their Maximum Health at the start of their turns. | Your creatures take damage equal to 40% of their Maximum Health at the start of their turns. |
| Resistant | Enemies cannot be afflicted with debuffs or lose stats. | Enemies cannot be afflicted with debuffs or lose stats. |
| Thorns | 50% of damage taken by enemies is reflected. The damage cannot exceed the enemies' Current Health. | 100% of damage taken by enemies is reflected. |
| Undying | Enemies resurrect after a short period of time. | Enemies resurrect after a short period of time. |
| Vengeance | When an enemy dies, all other enemies gain 30% stats. | When an enemy dies, all other enemies gain 50% stats. |